Congresses

Low immunogenicity of emicizumab in persons with haemophilia A

Schmitt C, Emrich T, Asikanius E, et al. Poster presentation ABS141.

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Safety and efficacy of emicizumab in persons with haemophilia A with/without FVIII inhibitors: Pooled data from four phase III studies (HAVEN 1–4)

Callaghan MU, Négrier C, Paz-Priel I, et al. Poster presentation ABS192.

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Evaluating the economic burden associated with problem joints, across moderate and severe haemophilia A, in children and adults: CHESS Paediatrics and CHESS II

Chowdary P, Hermans C, Asghar S, et al. Poster presentation ABS1148.

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An early view analysis of characteristics of persons with hemophilia Atreated with emicizumab using secondary claims data

Mahajerin A, Yang E, Patel AM, et al. Poster presentation.

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Changes in healthcare resource use and costs after emicizumab initiation for hemophilia A

Mahajerin A, Khairnar R, Meyer CS, et al. Poster presentation.

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Complications associated with central venous acceess devices in patients with hemophilia A: a secondary claims-base analysis

Orji C, Khairnar R, Patel AM, et al. Poster Presentation.

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Summary of thromboembolic (TE) or thrombotic microangiopathy (TMA) events in persons taking emicizumab

Lee L, Moreno K, Kuebler P, et al. Oral presentation P131.

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Final analysis of the STASEY trial: a single-arm, multicenter, open-label, Phase III clinical trial evaluating the safety and tolerability of emicizumab prophylaxis in persons with hemophilia A with factor VIII inhibitors

Jiménez-Yuste V, Peyvandi F, Klamroth R, et al. ISTH 2021; Poster presentation PB0521.

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Bone and joint health markers in persons with hemophilia A treated with emicizumab in HAVEN 3

Kiialainen A, Niggli M, Kempton C, et al. Oral presentation.

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Real-world treatment patterns, health outcomes, and healthcare resource use among persons with hemophilia A

Caplan EO, Patel AM, DeClue R, et al. Poster presentation 15.

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An insight into clinical outcomes in mild, moderate, and severe hemophilia A (HA): A preliminary analysis of the CHESS II study

Nissen F, Burke T, Asghar S, et al. Oral presentation OC 09.3.

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Effect of moderate and severe hemophilia A on daily life in children and their caregivers: A CHESS Paediatrics Study analysis

Khair K, Nissen F, Silkey M, et al. Oral presentation 147.

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Surgical experience from four phase III studies (HAVEN 1–4) of emicizumab in persons with haemophilia A (PwHA) with or without FVIII inhibitors

Santagostino E, Oldenburg J, Chang T, et al. Oral presentation OC 60.1.

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Patient access to hemophilia A treatment varies across US commercial health plans

Margaretos NM, Patel AM, Pranzer AD, et al. Poster presentation.

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Timing of treated spontaneous bleeding in persons with haemophilia A receiving emicizumab prophylaxis 6 mg/kg once every 4 weeks

Pipe SW, Ko RH, Chang T, et al. Poster presentation P191.

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Association of physical activity with bleeding frequency in children with hemophilia A: a CHESS PAEDs study analysis

Ofori-Asenso R, Nissen F, Silkey M, et al. ISTH 2021; Poster presentation PB0512.

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Estimating the risk of myocardial infarction in persons with hemophilia A using a machine-learning approach with US claims data

Faghmous I, Flores C, Sarouei K, et al. Poster presentation P-1133.

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Surgical experience from the Phase III STASEY trial of emicizumab prophylaxis in persons with haemophilia A (PwHA) with FVIII inhibitors: Data from the second interim analysis

Castaman G, Kremer Hovinga JA, Schutgens R, et al. Poster presentation PB0939.

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An analysis of fatalities in persons with congenital hemophilia A reported in the FDA Adverse Event Reporting System (FAERS) database

De Ford C, Kuebler P, Shang A, et al. Poster presentation 25.

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Real-world persistence with and adherence to emicizumab prophylaxis in persons with hemophilia A: a secondary claims database analysis

Mahajerin A, Khairnar R, Meyer CS, et al. Poster presentation 866.

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Emicizumab treatment is efficacious and well tolerated long term in persons with haemophilia (PwHA) with or without FVIII inhibitors: Pooled data from four HAVEN studies

Callaghan M, Negrier C, Paz-Priel I, et al. Oral presentation OC 60.2.

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A survey study of hematologists in the United States to understand disease management of patients with hemophilia A treated with emicizumab

Owens WE, Patel AM, Poulos K, et al. Poster presentation P205.

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Emicizumab in obese adults with hemophilia A - pooled data from three Phase III studies (HAVEN 1, 3 and 4)

Recht M, Mahlangu J, Minhas M, et al. ISTH 2021; Poster presentation PB0435.

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Factor VIII use in the treatment of breakthrough bleeds in hemophilia A patients without inhibitors on emicizumab prophylaxis: the phase 3 HAVEN 3 study experience

Callaghan M, Trzaskoma B, Ko RH, et al. Poster presentation P-2395.

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A contemporary framework for understanding mortality in people with congenital hemophilia A (PwcHA)

Pipe SW, Kruse-Jarres R, Mahlangu JN, et al. Poster presentation 23.

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Pharmacokinetics and coagulation biomarkers in persons with hemophilia A (PwHA) and FVIII inhibitors receiving emicizumab in the Phase IIIb STASEY study

Kiialainen A, Petry C, Jiménez-Yuste V, et al. Poster presentation PB0942.

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A phase IV, multicenter, open-label study of emicizumab prophylaxis in persons with hemophilia A with or without FVIII inhibitors undergoing minor surgical procedures

Escobar M, Dunn A, Quon D, et al. Poster presentation 1786.

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A single-arm, multicentre, open-label, phase III clinical trial to evaluate the safety and tolerability of prophylactic emicizumab in persons with haemophilia A (PwHA) with FVIII inhibitors (STASEY): Interim analysis results

Jiménez-Yuste V, Klamroth R, Castaman G, et al. Oral presentation OC 60.3.

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Estimating the burden of intracranial hemorrhage in persons with hemophilia A using administrative claims data.

Mahajerin A, Patel AM, Yang E, et al. Poster presentation P-2398.

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Associations between physical activity levels and bleeding frequency in people with mild, moderate, and severe hemophilia A (HA): A preliminary analysis of the CHESS II study

Nissen F, Burke T, Asghar S, et al. Poster presentation PB0943.

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Characteristics of persons with hemophilia A treated with emicizumab with or without factor VIII inhibitors

Mahajerin A, Yang E, Patel AM, et al. Poster presentation 31.

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Analysis of hemophilia A outcomes and treatment patterns using real-world data from the Canadian Hemophilia Bleeding Disorder Registry

Lee A, Germini F, Poon M, et al. Poster presentation 1793.

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Joint bleeds in paediatric patients with haemophilia A: A CHESS study analysis

Castro FA, Silkey M, Khair K, et al. Oral presenation OC 70.1.

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A systematic review of mortality statistics and causes of death in people with congenital hemophilia A (PwcHA)

Hay CR, Nissen F, Pipe SW. Poster presentation 32.

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Long-term safety and efficacy for up to >5 years in a phase 1/2 study in patients with severe hemophilia A

Shima A, Nagao A, Taki M, et al. Poster presentation PB0950.

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Safety and efficacy of emicizumab in persons with hemophilia A with or without FVIII inhibitors: pooled data from four phase III studies (HAVEN 1–4)

Callaghan MU, Négrier C, Paz-Priel I, et al. Poster presentation 1800.

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Analytical performance evaluation of a dedicated calibrator and controls for emicizumab quantification

Ramamurthy N, Kucharski C, McInerney M, et al. Oral presentation OC 07.4.

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Summary of thrombotic events or thrombotic microangiopathy events in persons taking emicizumab

Lee L, Moreno K, Kuebler P, et al. Poster presentation 35.

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A randomized, multicenter, open-label, Phase III clinical trial to evaluate the efficacy, safety, and pharmacokinetics of prophylactic emicizumab versus no prophylaxis in persons with hemophilia A in the Asia-Pacific region (HAVEN 5)

Wang S, Zhao X, Wang X, et al. Poster presentation PB0957.

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Problem joints and their clinical and humanistic burden in children and adults with moderate and severe hemophilia A: CHESS Paediatrics and CHESS II

McLaughlin P, Hermans C, Asghar S, et al. Poster presentation 2532.

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Early patient experiences with emicizumab in the United States: a qualitative study

Markowitz JT, Patel AM, Raimundo K, et al. Poster presentation PB0244.

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Second interim analysis results from the STASEY trial: A single-arm, multicenter, open-label, phase III clinical trial to evaluate the safety and tolerability of emicizumab prophylaxis in people with hemophilia A (PwHA) with FVIII inhibitors.

Jiménez-Yuste V, Klamroth R, Castaman G, et al. Poster presentation PB0958.

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Bone and joint health markers in persons with hemophilia A (PwHA) treated with emicizumab in the HAVEN 3 clinical trial

Kiialainen A, Niggli M, Kempton C, et al. Poster presentation 36.

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Real-world safety of emicizumab: The first interim analysis of the European Haemophilia Safety Surveillance (EUHASS) Database

Shang A, Bienz NS, Gadiraju R, et al. Poster presentation 2685.

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Evaluating patient and caregiver treatment preferences in hemophilia A using a discrete choice experiment

Benton M, Shi L, Patel AM, et al. Poster presentation PB0245.

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An insight into the impact of hemophilia A on daily life according to disease severity: A preliminary analysis of the CHESS II study

Noone D, Nissen F, Xu T, et al. Poster presentation 3449.

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Health-related quality of life in paediatric patients with haemophilia A

Castro FA, Silkey M, Khair K, et al. Poster presentation PB0250.

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Impact of hemophilia A inhibitor on joint health and health-related quality of life from the Hemophilia Utilization Group Studies Part VIII in the US

Ullmann MM, Manco-Johnson MJ, Roberts JC, et al. Poster presentation 3457.

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Exposure–response modeling of emicizumab for the prophylaxis of bleeding in haemophilia A patients with and without inhibitors against factor VIII

Jonsson F, Schmitt C, Petry C, et al. Poster presentation PB0325.

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Timing of treated spontaneous bleeding in persons with haemophilia A (PwHA) in the HAVEN 3 study

Mahlangu J, Oldenburg J, O'Connell N, et al. Poster presentation PB0694.

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Emicizumab prophylaxis improves long-term physical health scores in persons with haemophilia A (PwHA) with and without inhibitors: update from the HAVEN 3 and HAVEN 4 studies

Skinner M, Negrier C, Paz-Priel I, et al. Poster presentation PB0698.

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Treatment patterns and outcomes in persons with hemophilia A (PwHA): Analysis from the CHOICE survey in the United States

Patel AM, Cyhaniuk A, Raimundo K, et al. Poster presentation PB1404.

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Emicizumab pediatric experience in clinical studies and beyond

Levy G. Oral Presentation.

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Factor VIII use in the treatment of breakthrough bleeds in persons with hemophilia A without inhibitors on emicizumab prophylaxis: The phase III HAVEN 3 study experience

Callaghan M, Trzaskoma B, Ko RH, et al. Poster presentation.

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Early patient experiences with emicizumab in the United States: a qualitative study

Markowitz JT, Patel AM, Raimundo K, et al. Poster presentation.

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Congresses

The below Genentech/Roche-sponsored congress posters and oral presentations include data presented at scientific meetings from mid-2019 onwards. Click the below links for congress publications of interest.